tert-butyl N-[4-(hydroxyMethyl)phenyl]carbaMate - Names and Identifiers
Name | BOC-4-AMINOBENZYLALCOHOL
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Synonyms | 4-benzyl alcohol BOC-4-AMINOBENZYLALCOHOL 4-(Boc-aMino)benzyl alcohol tert-Butyl (4-(hydroxymethyl) TERT-BUTYL 4-(HYDROXYMETHYL)PHENYLCARBAMATE tert-butyl N-[4-(hydroxyMethyl)phenyl]carbaMate CarbaMic acid N-[4-(hydroxyMethyl)phenyl]-1,1-diMethyl ester Carbamic acid, N-[4-(hydroxymethyl)phenyl]-, 1,1-dimethylethyl ester
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CAS | 144072-29-7
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InChI | InChI=1/C12H17NO3/c1-12(2,3)16-11(15)13-10-6-4-9(8-14)5-7-10/h4-7,14H,8H2,1-3H3,(H,13,15) |
tert-butyl N-[4-(hydroxyMethyl)phenyl]carbaMate - Physico-chemical Properties
Molecular Formula | C12H17NO3
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Molar Mass | 223.27 |
Density | 1.161±0.06 g/cm3(Predicted) |
Melting Point | 74-76 °C |
Boling Point | 310.0±25.0 °C(Predicted) |
Flash Point | 141.313°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 13.66±0.70(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.565 |
tert-butyl N-[4-(hydroxyMethyl)phenyl]carbaMate - Introduction
BOC-4-AMINOBENZYLALCOHOL is an organic compound with the chemical formula C10H15NO3. It is a white crystalline solid, soluble in organic solvents such as methanol, ethanol and Ether solvents. The BOC-4-AMINOBENZYLALCOHOL has a certain stability and can be stored for a long time at room temperature.
BOC-4-AMINOBENZYLALCOHOL are often used as protecting groups in organic synthesis. It can be chemically reacted by reacting with an amino group to form a protected aminobenzyl alcohol to protect other reactive sites. It is widely used in the fields of synthetic drugs, peptides and organic molecules.
The preparation BOC-4-AMINOBENZYLALCOHOL can be carried out by a combination reaction and a deprotection reaction using methyl benzoate as a raw material. The specific step is to mix methyl benzoate and 4-aminobenzyl alcohol, and perform a combination reaction under alkaline conditions to generate BOC-4-AMINOBENZYLALCOHOL. The protecting group is then removed by a deprotection reaction to give the final product.
When using BOC-4-AMINOBENZYLALCOHOL, you need to pay attention to its safety. It may decompose at high temperatures to produce toxic gases, so contact with strong oxidants should be avoided. In the process of storage and use, attention should be paid to avoid contact with strong acids, strong bases and other substances to avoid unnecessary chemical reactions. At the same time, wear protective gloves and glasses during operation to ensure a good ventilation environment. If necessary, a comprehensive safety assessment and control measures should be carried out.
Last Update:2024-04-09 21:11:58